GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | trans | rs965513 | 1 | rs925489 | chr9:100546600 | GGT5 | chr22:24615623-24641110:- | 0.26 | 6.01 | 3.65E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs925489 | chr9:100546600 | LRRC42 | chr1:54412037-54433839:+ | -0.23 | -6.1 | 2.25E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs925489 | chr9:100546600 | NKX6-1 | chr4:85414436-85419387:- | 0.5 | 8.69 | 5.66E-17 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs925489 | chr9:100546600 | PLCE1 | chr10:95753746-96088146:+ | 0.27 | 6.23 | 1.01E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs1056667 | 1 | rs9295695 | chr6:26528250 | ZNF322B | chr9:99957633-99961910:- | -0.54 | -10.3 | 1.35E-22 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs9357010 | chr6:26527945 | ZNF322B | chr9:99957633-99961910:- | 0.55 | 10.43 | 4.54E-23 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs9393728 | chr6:26509330 | ZNF322B | chr9:99957633-99961910:- | 0.55 | 10.32 | 1.08E-22 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs9393729 | chr6:26514166 | ZNF322B | chr9:99957633-99961910:- | 0.54 | 10.3 | 1.35E-22 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs9393731 | chr6:26529374 | ZNF322B | chr9:99957633-99961910:- | 0.54 | 10.29 | 1.42E-22 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs9393732 | chr6:26530898 | ZNF322B | chr9:99957633-99961910:- | 0.54 | 10.29 | 1.42E-22 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs9461259 | chr6:26504835 | ZNF322B | chr9:99957633-99961910:- | 0.55 | 10.32 | 1.08E-22 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs9461271 | chr6:26554968 | ZNF322B | chr9:99957633-99961910:- | 0.57 | 11.17 | 6.6E-26 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs9467773 | chr6:26498426 | ZNF322B | chr9:99957633-99961910:- | 0.54 | 10.2 | 3.09E-22 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs9467774 | chr6:26505036 | ZNF322B | chr9:99957633-99961910:- | 0.55 | 10.32 | 1.08E-22 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs9467778 | chr6:26534743 | ZNF322B | chr9:99957633-99961910:- | 0.54 | 10.29 | 1.42E-22 | Educational attainment |